Description
LL37 is a 37-amino-acid cathelicidin peptide corresponding to the C-terminal fragment of human hCAP18, widely used as a reference antimicrobial and host-defence peptide in laboratory work. This listing supplies it as research-grade material for scientists working with research peptides in Canada, in a lyophilized single-use vial with documentation tied to the exact batch you receive. It is not a drug, supplement or therapeutic product and is not for human or veterinary use.
Overview
Each vial contains 5mg of LL37 as a lyophilized powder, sealed and intended for reconstitution in a solvent appropriate to your protocol. Lyophilization is the practical format for a cationic amphipathic peptide of this kind: the dry powder is far more stable in transit and in storage than a shipped solution, and it lets the researcher set concentration and buffer to suit the assay rather than working around a supplier’s choice. Available as a single vial or a box of ten for laboratories running extended or replicated work under a single lot. Every batch is analyzed by Janoshik, an independent analytical laboratory, with HPLC used to establish purity and mass spectrometry used to confirm identity. The resulting certificate of analysis is matched to the batch, not to the product line in general. Orders ship cold and discreetly from within Canada with nationwide tracking.
What it is known for
LL37 is known in the literature as the sole human cathelicidin-derived peptide, and it is one of the most frequently referenced host-defence peptides in microbiology and cell biology work. Buyers choose this listing for the documentation: independent third-party testing rather than in-house numbers, a certificate of analysis that corresponds to the vial in hand, and domestic Canadian dispatch that keeps a cold-chain product out of prolonged international transit and customs holds.
Key features
- Lyophilized 5mg vial — Dry powder is more stable than a pre-made solution during shipping and storage, and it leaves reconstitution volume, solvent and final concentration entirely under your control.
- Third-party HPLC purity testing (Janoshik) — An independent laboratory result carries more weight in a lab notebook or grant record than a supplier’s own assay, and it tells you what fraction of the material is the peptide rather than process residues.
- Mass spectrometry identity confirmation — Confirms the molecular mass matches LL37 — the check that distinguishes the correct 37-residue sequence from a mislabelled, truncated or substituted product.
- Batch-matched certificate of analysis — The paperwork corresponds to the specific lot you are sent, so results can be traced back to characterized material if an experiment needs to be defended or repeated.
- Single vial or box of ten — Buy one vial for a pilot or method development, or ten from a single lot when a study series needs to eliminate batch-to-batch variability as a variable.
- Cold storage and cold shipping — Peptide material is handled at temperature from the shelf onward, so what arrives reflects the condition the certificate describes.
- Domestic Canadian dispatch with tracking — Shorter transit, no cross-border customs delay for a temperature-sensitive item, and a tracking number so receipt can be logged.
- Discreet, sealed packaging — Arrives without describing its contents externally, and the seal makes tampering evident on receipt.
Benefits
- Documentation you can cite: independent purity and identity data tied to your specific batch
- Full control of buffer, solvent and working concentration from a dry starting material
- Reduced experimental noise when replicate work is run from one lot
- Predictable Canadian delivery for a product that should not sit in transit
- Clear labelling of research-only status for institutional receiving and compliance records
Specifications
| Detail | Value |
|---|---|
| Product | LL37 |
| SKU | PP-LL37 |
| Format | Lyophilized powder for reconstitution |
| Sizes | 5mg (1 vial); 5mg (box of 10) |
| Purity testing | HPLC, third-party (Janoshik) |
| Identity testing | Mass spectrometry, third-party (Janoshik) |
| Documentation | Batch-matched certificate of analysis |
| Category | Recovery & Repair |
| Origin of shipment | Canada, tracked nationwide |
| Intended use | In-vitro laboratory research only |
Typical applications
- In-vitro antimicrobial and host-defence peptide studies
- Cell culture work involving cathelicidin-family peptides
- Membrane interaction and peptide structure investigations
- Reference or comparator material in peptide screening panels
- Analytical method development and instrument calibration work
Important information
- Research use only. Not a drug, supplement, food or cosmetic. Not for human or veterinary use, ingestion or administration.
- Keep the vial cold and sealed until use; reconstitute only when the material is needed.
- Choose a reconstitution solvent appropriate to your assay — LL37 is a cationic, amphipathic peptide and solvent choice affects both solubility and behaviour in solution.
- Record the lot number on receipt so results stay linked to the matching certificate of analysis.
- Handle in a laboratory setting with appropriate personal protective equipment and institutional protocols.
- Inspect packaging on arrival and confirm the seal is intact before logging the vial into inventory.
Common questions
What testing is done, and by whom?
Each batch is tested by Janoshik, an independent analytical laboratory. HPLC establishes purity and mass spectrometry confirms identity. The certificate of analysis issued from that testing is matched to the batch supplied.
How is it supplied?
As a lyophilized powder in a sealed vial containing 5mg, available singly or in a box of ten. It requires reconstitution in a solvent suited to your protocol before use.
Why buy the box of ten?
Ten vials drawn from one production lot let a multi-stage or replicated study run without batch variation confounding the results, and reduce repeat ordering during a long project.
How should the vial be stored?
Cold and sealed, as received. It is stored cold here and shipped cold, so it should go into cold storage promptly on arrival and be reconstituted only when needed.
Can I get the certificate of analysis for my batch?
Yes. A batch-matched certificate is available for the lot you receive, so your records can reference the tested material rather than a generic product specification.
Is this suitable for human or animal use?
No. It is sold strictly as an in-vitro laboratory research reagent and is not a drug, supplement, food or cosmetic. It is not intended to diagnose, treat, cure or prevent any disease and must not be administered to humans or animals.
In summary
LL37 supplied the way a research reagent should be: lyophilized, independently tested for purity and identity, documented against the batch you receive, and shipped cold and tracked from within Canada. Order a single 5mg vial for initial work, or a box of ten to keep an extended study on one lot.
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