Coremend (TB500/KPV/BPC157)

Description

Coremend is a pre-combined repair-peptide reagent for laboratories running tissue-repair, inflammation and recovery models. It brings TB-500, KPV and BPC-157 together in one lyophilized vial at 25 mg + 10 mg + 10 mg, so a study protocol that would otherwise call for three separate reconstitutions, three sets of dilutions and three purity records is handled by a single vial with a single batch-matched certificate of analysis. It is stocked and shipped from within Canada for researchers who want research peptides Canada-wide without a cross-border customs hold sitting between order and bench.

Overview

Each unit is supplied as a sterile-filled lyophilized powder in a sealed vial, intended for reconstitution in a suitable research solvent chosen by the investigator — typically bacteriostatic or sterile water for the peptide fraction, depending on the assay. The three components are dosed to a defined specification: 25 mg TB-500 (thymosin beta-4 fragment), 10 mg KPV (the C-terminal alpha-MSH tripeptide lysine-proline-valine) and 10 mg BPC-157 (the pentadecapeptide body protection compound). Because the ratio is fixed at fill, reconstitution volume alone determines the concentration of all three, which keeps the relative proportions constant across every dilution series drawn from the vial. Available as a single vial or a box of ten for extended or multi-arm work.

What it is known for

Buyers know Coremend as the combined form of the three peptides most often cited together in repair and inflammation literature — TB-500 for actin-binding and cell-migration research, BPC-157 for gastrointestinal and connective-tissue models, and KPV for its anti-inflammatory signalling work. The appeal is consolidation with documentation: one vial, one lot number, one Janoshik report covering HPLC purity and mass-spectrometry identity, rather than reconciling three certificates from three suppliers with three different fill dates.

Key features

• Fixed 25 mg + 10 mg + 10 mg fill — The ratio between the three peptides is set before you touch the vial, so every aliquot and every dilution carries the same proportions — one less variable to control for when interpreting results.
• Third-party analysis by Janoshik — Purity and identity are confirmed by an independent lab rather than in-house, which is what a reviewer or supervisor will ask for when the data is questioned.
• HPLC purity plus mass-spectrometry identity — HPLC tells you how much of the material is the peptide; MS confirms it is the right peptide. Together they close both gaps a single test would leave open.
• Batch-matched certificate of analysis — The COA corresponds to the lot in your hand, not a representative sample from a past run, so it can be filed directly against the experiment it supported.
• Lyophilized powder format — Freeze-dried peptide is far more stable in transit and in storage than solution, and it lets you set your own working concentration instead of accepting the supplier’s.
• Cold-stored and shipped domestically from Canada — Material stays under temperature control until dispatch and moves on tracked domestic transit, avoiding the long unrefrigerated customs delays that international peptide orders are prone to.
• Single vial or box of ten — Run a pilot on one vial and scale to a full study on the same specification and, where lots allow, the same batch — consistency across a long protocol without re-validating a new source.

Benefits

• One reconstitution instead of three, cutting handling steps and the contamination and pipetting error that come with them.
• A complete analytical paper trail per lot, ready for internal QA, grant reporting or method sections.
• Consistent inter-peptide ratios across a study, which makes comparisons between runs meaningful.
• Shorter, tracked domestic transit, so the vial spends less time in ambient conditions before it reaches the freezer.
• Predictable procurement for multi-phase work through the ten-vial format.

Specifications

Typical applications

• In-vitro tissue-repair and wound-model research
• Inflammation and cytokine-signalling studies
• Cell migration, proliferation and connective-tissue assays
• Comparative work assessing combined versus single-peptide exposure
• Method development and analytical reference work requiring a documented multi-peptide reagent

Important information

• Research use only. Not for human or veterinary use, ingestion or administration, and not intended to diagnose, treat, cure or prevent any disease.
• Keep the sealed vial cold and protected from light until use; reconstitute only what the protocol requires.
• Choose your reconstitution solvent to suit the assay — solvent choice affects both stability and downstream compatibility.
• Request the batch-matched COA and check the lot number on the vial against it before the material enters a study.
• Reconstituted peptide is less stable than lyophilized powder; store cold after reconstitution and plan aliquoting accordingly.
• Because the three peptides share one vial, they cannot be dosed independently — use single-peptide reagents where the protocol needs separate control of each component.

Common questions

What exactly is in the vial?

25 mg TB-500, 10 mg KPV and 10 mg BPC-157, combined and freeze-dried together as a single lyophilized cake.

Can I get the certificate of analysis for my specific lot?

Yes. Every batch is tested independently by Janoshik and a batch-matched COA covering HPLC purity and mass-spectrometry identity is available for the lot supplied.

How is it reconstituted?

With a suitable research solvent selected by the investigator, commonly bacteriostatic or sterile water. Total reconstitution volume sets the concentration of all three peptides at once, since the ratio is fixed at fill.

Why choose the blend over buying the three peptides separately?

Fewer handling steps, a fixed and reproducible ratio across every dilution, and one lot with one set of analytical documents rather than three. If your protocol needs to vary the peptides independently, buy them separately instead.

How does it ship and how is it stored?

Cold-stored and dispatched from Canada in discreet, tracked packaging. Keep the sealed vial cold on arrival.

Who can buy this?

Qualified research buyers — laboratories, universities, biotech companies and researchers purchasing for in-vitro laboratory work. It is not sold for human or veterinary use.

In summary

Coremend puts TB-500, KPV and BPC-157 into one documented, independently tested lyophilized vial, with the analytical record to back the lot and domestic Canadian shipping to get it to the bench cold and quickly. If your repair or inflammation model calls for all three at a fixed ratio, it removes three sets of handling and paperwork from the protocol.