Description
Hexarelin (examorelin) is a GHRP-6 analogue with a single methylated tryptophan, and one of the most potent growth-hormone secretagogues in the GHRP family. It also binds the cardiac receptor CD36, which made it a tool in heart research. Pure Peptides Canada supplies it as a lyophilized research reagent in 3 mg vials, with an independent Janoshik HPLC and mass-spectrometry report, CAD pricing and tracked shipping from inside Canada.
Hexarelin at a glance
- What it is: His-D-2-methyl-Trp-Ala-Trp-D-Phe-Lys-NH2, GHRP-6 with a methyl group added to its D-tryptophan for greater potency and stability.
- What researchers study: GHS-R1a potency and desensitization, and CD36-mediated effects in heart models that do not depend on growth hormone.
- Evidence level: cell, animal and human pharmacology studies. Never approved as a medicine.
- Supplied as: sealed lyophilized powder, 3 mg, single vial or box of 10.
- Delivery: ships from inside Canada by tracked Xpresspost in 3–7 days ($25 CAD), or free in 4–12 days on orders over $299.
Hexarelin
Examorelin · EP-23905 · methylated GHRP-6 analogue
- His
- D-2MeTrp
- Ala
- Trp
- D-Phe
- Lys
- NH₂
Blue: modified and D-amino acids. The methylated D-tryptophan at position 2 is the only change from GHRP-6.
- Length
- 6 amino acids, C-terminal amide
- Molecular formula
- C47H58N12O6
- Molecular weight
- ≈ 887 g/mol
- CAS number
- 140703-51-1
- Targets
- Ghrelin receptor (GHS-R1a) and CD36
- Form
- Lyophilized powder, sealed vial
- Sizes
- 3 mg (single or box of 10)
- SKU
- PP-HEXARELIN
Where the evidence stands
- Cell studies
- Animal models
- Human studies
- Approved medicine
Human data comes from pharmacology studies. Hexarelin is not an approved medicine anywhere.
What is hexarelin?
In the early 1990s, Romano Deghenghi and colleagues in Europe set out to improve on GHRP-6. Adding a single methyl group to the D-tryptophan at position 2 produced hexarelin, which released growth hormone more strongly in human and animal studies. It also showed a feature that became a research topic of its own: with repeated exposure the growth-hormone response fades, a form of receptor desensitization.
Hexarelin’s second identity came from heart research. Studies found it binds CD36, a scavenger receptor on heart and blood-vessel cells, and protects heart tissue in animal injury models even in animals lacking growth hormone. That separates its cardiac effects from its pituitary ones and makes it useful for studying receptor pathways beyond GHS-R1a.
What hexarelin research looks at
- Secretagogue potency: growth-hormone release compared with GHRP-6, GHRP-2 and ipamorelin.
- Desensitization: how responses fade with repeated GHS-R1a stimulation.
- CD36 signalling: cardioprotection in ischaemia and heart-failure models.
- Stress-axis effects: cortisol and prolactin responses alongside growth hormone.
Regulatory status: hexarelin is not an authorized drug in Canada, and growth-hormone secretagogues are on the World Anti-Doping Agency prohibited list. We sell it strictly as a laboratory reagent for in-vitro research.
Why researchers order hexarelin from Pure Peptides Canada
Add a 3 mg vial or a box of 10 above. Orders over $299 ship free across Canada.
See lab resultsHexarelin FAQ
Where can I buy hexarelin in Canada?
Pure Peptides Canada stocks hexarelin as a lyophilized research reagent in 3 mg vials and ships it from inside Canada by tracked Xpresspost in 3–7 days ($25 CAD), or free in 4–12 days on orders over $299.
What is the difference between hexarelin and GHRP-6?
One methyl group. Hexarelin is GHRP-6 with a methylated D-tryptophan at position 2, which increases its potency in study models. See our GHRP-6 vs GHRP-2 vs hexarelin comparison.
Why is hexarelin studied in heart research?
It binds CD36, a receptor on heart and vascular cells, and showed protective effects in animal heart-injury models independent of growth hormone. That research is preclinical.
Is this hexarelin third-party tested?
Yes. An HPLC purity and mass-spectrometry identity report from Janoshik Analytical, an independent lab, is listed on our Lab Testing page. Our COA guide explains how to read it.
Is hexarelin approved in Canada?
No. Hexarelin is not an authorized drug in Canada or elsewhere. It is sold here only as a laboratory reagent for in-vitro research.
Can hexarelin be used in people or animals?
No. This product is for in-vitro laboratory research only and is not a drug, supplement or food. We do not provide dosing or administration information.
For laboratory research use only. Not a drug, supplement, food or cosmetic, not for human or veterinary use, and not intended to diagnose, treat, cure or prevent any disease.
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