CJC1295 DAC

Description

CJC-1295 DAC is a synthetic growth hormone-releasing hormone (GHRH) analogue used as a reference reagent in laboratory work on somatotropic axis signalling. For labs sourcing research peptides in Canada, this is the DAC-modified version of CJC-1295 — the variant carrying a Drug Affinity Complex group, which distinguishes it from the shorter-acting modified GRF (1-29) sold under the same base name. It is supplied as a lyophilized powder for reconstitution in a suitable research solvent, for in-vitro use only.

Overview

Each vial contains 5mg of CJC-1295 DAC as a lyophilized cake or powder, sealed under vacuum and stoppered for reconstitution at the bench. CJC-1295 is a tetrasubstituted analogue of the first 29 amino acids of GHRH; the DAC addition is a maleimidopropionic acid group that covalently conjugates to circulating albumin, which is the structural feature behind the extended plasma presence that separates this compound from non-DAC GRF analogues in study design. Available as a single vial or a box of ten for multi-arm or repeat work, it ships cold and discreetly from within Canada with nationwide tracking. Research use only.

What it is known for

Buyers know CJC-1295 DAC as the long-acting arm of the CJC-1295 family — the version chosen when a protocol calls for sustained GHRH-receptor engagement rather than the pulsatile profile of modified GRF (1-29). The practical reason labs specify it from a tested supplier is identity: DAC and non-DAC material are frequently mislabelled in the grey market, and a mass spectrometry result on the exact batch in hand is the only way to confirm the conjugate is actually present. Every lot here carries independent Janoshik analysis rather than an in-house or reused certificate.

Key features

• Batch-matched third-party COA (Janoshik) — The purity and identity figures correspond to the lot in your vial, not to a representative sample, so results are traceable and defensible in a write-up.
• HPLC purity analysis — Quantifies related-substance and truncated-sequence content, letting you judge whether observed activity comes from the intended compound or from impurities.
• Mass spectrometry identity confirmation — Confirms the molecular mass consistent with the DAC-conjugated structure, ruling out substitution with the cheaper non-DAC analogue.
• Lyophilized presentation — Dry peptide is far more stable in storage and transit than solution, and lets you set your own concentration and buffer for the assay.
• Drug Affinity Complex modification — The albumin-binding group gives a prolonged exposure profile in vitro and in model systems, suitable for studies where sustained receptor occupancy rather than a short pulse is the variable of interest.
• 5mg vial, single or box of ten — One vial suits pilot and characterization work; the ten-pack keeps a single lot number across an entire study, removing batch variation as a confounder.
• Cold-chain handling, shipped from Canada — Domestic dispatch avoids customs delays and prolonged ambient exposure, and shipments are tracked nationwide.

Benefits

• You can verify what you received before you use it, rather than trusting a product label
• Consistent lot material across a multi-condition study when you order the box of ten
• Freedom to choose solvent, concentration and aliquot scheme to suit your protocol
• Reduced risk of confusing DAC and non-DAC material in a study that depends on the difference
• Faster, more predictable delivery than international ordering, with cold handling maintained

Specifications

Typical applications

• In-vitro studies of GHRH receptor binding and signalling
• Comparative work against modified GRF (1-29) and other GHRH analogues
• Somatotropic axis and growth-signalling pathway research
• Analytical method development, reference standard and assay calibration work
• Peptide stability, reconstitution and formulation studies

Important information

• Confirm the certificate of analysis lot number matches the number printed on your vial before use.
• Store the sealed lyophilized vial cold and protected from light; keep it dry until the moment of reconstitution.
• Reconstitute with a solvent appropriate to your assay, aliquot to avoid repeat freeze-thaw cycles, and treat reconstituted material as considerably less stable than the dry powder.
• Check whether your protocol calls for the DAC or non-DAC form — they are not interchangeable, and the extended exposure profile of DAC material will change study timelines.
• This product is not a drug, supplement, food or cosmetic. It is not for human or veterinary use, ingestion or administration, and is not intended to diagnose, treat, cure or prevent any disease.

Common questions

What is the difference between CJC-1295 DAC and CJC-1295 without DAC?

Both are based on the first 29 amino acids of GHRH. The DAC version carries a Drug Affinity Complex group that conjugates to albumin, giving a much longer exposure window. The non-DAC form, usually sold as modified GRF (1-29), acts over a far shorter period. Choose based on whether your design needs sustained or pulsatile receptor engagement.

What does the certificate of analysis show?

HPLC purity and mass spectrometry identity for the specific batch you receive, issued by Janoshik, an independent analytical laboratory. It is batch-matched, so the lot number on the document corresponds to the number on your vial.

How should I reconstitute and store it?

Keep the sealed vial cold and dry until use. Reconstitute with a research solvent suited to your assay, then aliquot into single-use volumes and store cold. Repeated freeze-thaw cycles degrade peptides, so plan aliquot sizes around your working volume.

Why order the box of ten?

A ten-vial box lets you run an entire study on one lot. That removes batch-to-batch variation as a variable and means one certificate of analysis covers all the material in the project.

Do you ship across Canada?

Yes. Orders are dispatched from Canada with discreet packaging and nationwide tracking, so material stays domestic and avoids customs holds.

Can this be used on humans or animals?

No. It is supplied strictly for in-vitro laboratory research by qualified buyers, and is not a drug, supplement or medical product of any kind.

In summary

A DAC-conjugated GHRH analogue supplied as a 5mg lyophilized vial, with independent HPLC and mass spectrometry results tied to the batch you receive. For researchers who need confirmed identity on a compound that is often mislabelled, and reliable domestic delivery, it is a straightforward choice. Research use only.