MOTS-c

Description

MOTS-c is a mitochondrial-derived peptide widely used as a reference compound in cellular and metabolic research. This listing is for a laboratory reagent — a lyophilized vial intended for in-vitro work by qualified investigators, and one of the mitochondrial and cellular-signalling research peptides Canada-based labs order most often alongside their metabolic panels. It is not a drug, supplement or therapeutic product, and it is not supplied for human or veterinary use.

Overview

MOTS-c (mitochondrial open reading frame of the twelve S rRNA type-c) is described in the literature as a short peptide encoded within the mitochondrial genome rather than the nuclear genome, which is why it appears so frequently in work on mitochondrial-nuclear signalling, cellular energy metabolism and age-related cellular research. The reagent is supplied as a lyophilized powder in a sealed vial, ready for reconstitution in a suitable research solvent chosen by the end user. Sizes are 10 mg, 20 mg and 40 mg, each available as a single vial or a box of ten for labs running extended assay series or replicate arms. Vials ship cold from within Canada, tracked and discreetly packaged, so material clears customs before it reaches you rather than after.

What it is known for

Buyers know this product for two things: the analytics and the origin of the material. Each batch is sent to Janoshik, an independent third-party analytical laboratory, for purity determination by HPLC and identity confirmation by mass spectrometry, and the certificate of analysis you receive is matched to the batch in your hand — not a generic document reused across production runs. That matters because peptide reagents are only as reliable as their characterization; an unverified vial makes every downstream result arguable. Combined with domestic Canadian shipping, it removes the two most common failure points in peptide sourcing: unverifiable identity and unpredictable border delays.

Key features

• Lyophilized powder format — Freeze-dried material is far more stable in transit and long-term storage than a solution, and it lets the researcher set their own solvent and concentration rather than inheriting someone else’s formulation.
• Independent HPLC purity testing — Quantifies how much of the vial contents is the intended peptide versus process-related impurities, so purity is a number you can cite in your methods rather than a marketing adjective.
• Mass spectrometry identity confirmation — Confirms the molecular mass matches the expected peptide, guarding against mislabelled or substituted material — the failure mode that silently invalidates an entire experiment.
• Batch-matched certificate of analysis — Ties the analytical data to the specific lot you received, which is what internal QA, supervisors and reviewers actually want to see.
• Third-party analysis by Janoshik — The testing is not performed in-house by the seller, so the purity and identity results are not self-reported.
• Three vial sizes plus ten-packs — Lets you match the quantity to the scale of the study — a single 10 mg vial for pilot or method-development work, boxes of ten where consistency across a long series of runs matters.
• Cold storage and domestic Canadian dispatch — Material is held and shipped under cold conditions on a tracked domestic route, shortening transit and avoiding the temperature and clearance uncertainty of cross-border shipments.
• Sealed single-use vials — Each vial is opened once at the point of reconstitution, limiting moisture ingress and cross-contamination between preparations.

Benefits

• Results you can defend, because purity and identity are documented per batch by an outside lab
• Less experimental variance across a study when you order matched vials from the same production run
• Faster, more predictable delivery within Canada, with tracking from dispatch to door
• Freedom to choose your own solvent, buffer and working concentration for your assay design
• Documentation ready for institutional QA, procurement and record-keeping without chasing the supplier for paperwork

Specifications

Typical applications

• In-vitro studies of mitochondrial-derived peptides and mitochondrial-nuclear signalling
• Cell-culture work on energy metabolism and cellular stress response
• Cellular ageing and longevity research programs
• Reference or comparator material in peptide assay development
• Method development, HPLC system suitability and analytical validation work

Important information

• Research use only. Not a drug, supplement, food or cosmetic. Not for human or veterinary use, ingestion or administration, and not intended to diagnose, treat, cure or prevent any disease.
• Keep vials cold and sealed until use; return unopened stock to cold storage promptly after delivery.
• Reconstitute with a solvent appropriate to your protocol and handle the peptide under conditions suited to your assay — solvent choice, concentration and storage of the reconstituted solution are the end user’s responsibility.
• Request or download the certificate of analysis for your lot and check that the batch number on the document matches the vial.
• Avoid repeated freeze-thaw cycles of reconstituted material where your protocol allows; aliquot instead.
• Order from a single batch where cross-run consistency matters to your study design.

Common questions

What form does MOTS-c arrive in?

As a lyophilized (freeze-dried) powder in a sealed vial. It contains no solvent, so you reconstitute it yourself with the solvent your protocol calls for.

Who performs the testing?

Janoshik, an independent third-party analytical laboratory. Purity is measured by HPLC and identity confirmed by mass spectrometry, and the certificate of analysis is matched to your batch rather than being a generic document.

Which size should I order?

A single 10 mg vial suits pilot work or method development. Larger vials or a box of ten make sense for extended assay series, replicate arms or multi-month projects where you want the material to come from a consistent batch.

Where does it ship from?

From within Canada, tracked and discreetly packaged, so the order does not cross a border on its way to you.

Can this be used in humans or animals?

No. It is supplied strictly for in-vitro laboratory research by qualified personnel. It is not approved as a drug or supplement and must not be ingested or administered.

How should I store it before use?

Keep the sealed vial cold and protected from moisture and light until you are ready to reconstitute. Once in solution, storage conditions and shelf life depend on your solvent and protocol.

In summary

A characterized MOTS-c reagent for in-vitro research — lyophilized for stability, independently tested for purity and identity, documented per batch, and shipped cold and tracked within Canada. Choose the vial size that matches your study, and keep the certificate of analysis with your records. Research use only.