Peptide Names Decoded: Where BPC-157, TB-500, GHRP-6 and -relin Come From
Peptide names decoded: why it's called BPC-157, what INN stems like -relin and -glutide mean, how code names arise, and why a name never proves identity.
Archive
Tag: Peptide Science
Plain-English explainers on peptide fundamentals: amino acids, structure, receptors, stability and how peptides are made.
Peptide Sequence Notation and End Caps: Reading Ac-, -NH2, cyclo and Salt Forms
Peptide sequence notation decoded: H-/-OH and Ac-/-NH2 termini, cyclo and disulfide bridges, non-standard residues and salt forms, plus what end caps do.
Peptides vs Small Molecules: What Actually Differs in the Lab
Peptides vs small molecules: size, synthesis, stability, analysis and how each reaches its target, and why a peptide catalogue also lists non-peptides.
Scrambled Peptide Controls: How to Design a Credible Peptide Experiment
What a scrambled peptide control tests, how to design one, when alanine scans or inactive analogues work better, and the pitfalls that undermine controls.
Cyclic AMP and Protein Kinase A Explained
How a peptide signal outside a cell becomes a response inside it: adenylyl cyclase, cyclic AMP, protein kinase A and CREB, why GHRH analogues and growth hormone secretagogues use different routes, and what the cascade diagram leaves out.
α-MSH and the Melanocortin System Explained
What alpha-MSH is, how one precursor protein yields it alongside ACTH and beta-endorphin, what each of the five melanocortin receptors actually responds to, and where KPV fits as its C-terminal fragment.
NF-κB Explained: The Switch Behind Inflammation Research
What NF-kB actually is, how IkB and the IKK complex throw the switch, why no direct NF-kB inhibitor has been approved, and what the published KPV, LL-37 and GHK-Cu work really measured.
Cerebrolysin: What the Evidence Actually Shows
What Cerebrolysin is, why a mixture of brain-derived peptides cannot be characterised like a single research peptide, and what the Cochrane reviews of stroke and vascular dementia actually concluded.
Amylin: The Other Hormone Beta Cells Release
Amylin explained: the 37-amino-acid hormone co-secreted with insulin, how it was found in pancreatic amyloid deposits, why the human form clumps, how its receptors are assembled, and the analogues now in trials.
Brown Adipose Tissue and Thermogenesis
How adult human brown fat was confirmed in 2009, what UCP1 actually does, why FDG-PET does not measure heat production, how little energy brown fat is measured to burn, and why none of the compounds sold as thermogenic acts on it.
