Research Peptide Glossary: 46 Terms Every Lab Should Know
Plain-English definitions of 46 research-peptide terms, from HPLC, mass spectrometry and COAs to counter-ions, net peptide content, molarity, RUO and DIN, grouped by topic.
Archive
Tag: Buy Peptides Canada
Guides for Canadian labs buying research peptides: how to compare suppliers, read certificates of analysis and source compounds for in-vitro research.
Neurotrophic Factors: NGF, BDNF and the Neurogenesis Question
What NGF and BDNF are, why precursor forms do the opposite of mature ones, why adult human neurogenesis is still contested, and exactly what the published Semax, Selank and P021 work measured.
Cyclic AMP and Protein Kinase A Explained
How a peptide signal outside a cell becomes a response inside it: adenylyl cyclase, cyclic AMP, protein kinase A and CREB, why GHRH analogues and growth hormone secretagogues use different routes, and what the cascade diagram leaves out.
α-MSH and the Melanocortin System Explained
What alpha-MSH is, how one precursor protein yields it alongside ACTH and beta-endorphin, what each of the five melanocortin receptors actually responds to, and where KPV fits as its C-terminal fragment.
NF-κB Explained: The Switch Behind Inflammation Research
What NF-kB actually is, how IkB and the IKK complex throw the switch, why no direct NF-kB inhibitor has been approved, and what the published KPV, LL-37 and GHK-Cu work really measured.
Sirtuins Explained: SIRT1 to SIRT7
The seven mammalian sirtuins, why NAD+ is consumed rather than used as a cofactor, the replication failure that reset the lifespan claims, the resveratrol assay artefact, and what the SIRT1-FOXO4 link does and does not imply.
Brown Adipose Tissue and Thermogenesis
How adult human brown fat was confirmed in 2009, what UCP1 actually does, why FDG-PET does not measure heat production, how little energy brown fat is measured to burn, and why none of the compounds sold as thermogenic acts on it.
Nrf2 and Oxidative Stress Explained
What oxidative stress actually means, how the Keap1-Nrf2 switch works, why Nrf2 controls glutathione synthesis, what happened when antioxidants and an Nrf2 activator were put into large trials, and why the GHK-Cu Nrf2 claim does not hold up.
mTOR Explained: The Cell’s Growth Switch
What mTOR is, how a soil bacterium from Easter Island led to it, the difference between mTORC1 and mTORC2, what the mouse lifespan data actually said, and why rapamycin is not the clean mTORC1 inhibitor it is often described as.
Somatostatin: The Brake on Growth Hormone
The inhibitory half of the growth hormone axis: what somatostatin is, the five receptors it works through, why its three-minute half-life produced octreotide, and why the claim that GHRPs suppress it is not supported.
