New to research peptides? This glossary defines the terms you’ll meet on listings and Certificates of Analysis โ in plain English.
Quality & testing
Certificate of Analysis (COA) โ A lab document reporting the measured quality of a specific batch: purity, identity, and other parameters. Should be batch-specific.
HPLC (High-Performance Liquid Chromatography) โ A method that separates a sample to measure purity, shown as peaks on a chromatogram.
Mass spectrometry (MS) โ Measures molecular mass to confirm identity (the molecule is what the label says).
Purity โ The percentage of the target peptide among peptide-related species, by HPLC. A common high standard is โฅ99%.
Net peptide content โ How much of the vial’s mass is actually peptide (vs. salt and water); often 80โ95%.
Chromatogram โ The graph from HPLC; one tall, sharp peak signals high purity.
Third-party / accredited lab โ An independent, audited lab whose results are more credible than in-house figures.
Composition & form
Lyophilized โ Freeze-dried into a stable powder by removing most water.
Counter-ion โ The salt form a peptide ships in, usually acetate or TFA (trifluoroacetate); affects net peptide content.
Karl Fischer (KF) โ A titration that measures residual water in the powder.
Endotoxin โ Bacterial contaminants sometimes reported on a COA; lower is better.
Sequence โ The ordered chain of amino acids that defines the peptide.
Molecular weight (MW) โ The mass of one mole of the compound (g/mol); needed to convert to molar units.
Concentration math (in-vitro)
Molarity (M) โ Moles per litre; counts molecules. mM = millimolar, ยตM = micromolar.
Stock solution โ A concentrated solution you later dilute.
Dilution (CโVโ = CโVโ) โ The equation for making a weaker solution from a stronger one.
mg/mL โ Milligrams of solute per millilitre of solvent; a mass-per-volume concentration.
Logistics
Batch / lot number โ A code identifying a production run; match it to your COA and vial.
Cold-chain โ Temperature-controlled handling/shipping for products that need it.
Research use only (RUO) โ Sold strictly for laboratory research; not for human or veterinary use.
Key takeaways
- HPLC = purity, MS = identity, COA = the batch report tying it together.
- Lyophilized powder is stable when kept cold, dark and dry.
- Net peptide content and counter-ion explain what’s really in the vial.
FAQ
What does “lyophilized” mean in one sentence? Freeze-dried into a dry, stable powder by removing water.
What’s the difference between mM and ยตM? 1 mM = 1000 ยตM. Both are molar concentrations; mM is a thousand times stronger than ยตM.
What does RUO mean? Research use only โ the product is for laboratory research, not for human or veterinary use.
Browse verified research peptides
Every batch we ship is independently tested by Janoshik Analytical โ HPLC for purity, mass spectrometry for identity โ with a batch-matched Certificate of Analysis you can verify yourself. Browse the catalog โ ยท See the latest COAs โ
*For laboratory and research use only. Not for human or veterinary use, consumption, or administration. Nothing in this article is medical advice or a claim that any compound treats, cures, or prevents any condition.*