Description
HGH Fragment 176-191 is a 16-residue peptide from the C-terminal end of human growth hormone, the region that early research linked to the hormone’s effects on fat metabolism. It is used to study that activity apart from growth signalling. Pure Peptides Canada supplies it as a lyophilized research reagent in 5 mg vials, with CAD pricing and tracked shipping from inside Canada.
HGH Fragment 176-191 at a glance
- What it is: a synthetic peptide matching residues 176 to 191 of human growth hormone, with an internal disulfide bridge.
- Why it is studied: to isolate growth hormone’s lipolytic (fat-breakdown) region from its growth-promoting and IGF-1-raising activity.
- Relation to AOD-9604: AOD-9604 is a closely related stabilized version of the same region that went through human trials.
- Supplied as: sealed lyophilized powder, 5 mg, single vial or box of 10.
- Delivery: ships from inside Canada by tracked Xpresspost in 3–7 days ($25 CAD), or free in 4–12 days on orders over $299.
HGH Fragment 176-191
hGH(176-191) · C-terminal growth hormone fragment · lipolytic fragment
- Length
- 16 amino acids
- Source region
- C-terminus of 191-residue human growth hormone
- Structure
- One internal disulfide bond between two cysteines
- Molecular weight
- ≈ 1.8 kDa; see the lab report for the measured mass
- Form
- Lyophilized powder, sealed vial
- Sizes
- 5 mg (single or box of 10)
- SKU
- PP-HGH176191
Where the evidence stands
- Cell studies
- Animal models
- Controlled human trials
- Approved medicine
Human trials were run on the related AOD-9604 and did not show benefit for obesity. This fragment is not an approved medicine.
What is HGH Fragment 176-191?
Growth hormone does two things at once: it promotes growth, largely through IGF-1, and it mobilizes fat. In the 1990s researchers at Monash University in Melbourne showed that the C-terminal end of the hormone carried much of the fat-metabolism activity. Synthetic peptides covering residues 176 to 191 increased fat breakdown and reduced fat formation in rodent fat tissue without raising IGF-1 or blood glucose.
That work led directly to AOD-9604, a stabilized version of the same region that was taken into human trials for obesity and did not beat placebo. HGH Fragment 176-191 remains a research tool for studying the lipolytic region of growth hormone, usually alongside AOD-9604. Because naming in the research market varies, the measured mass on the lab report is the best way to confirm what a vial contains.
Testing note: lab reports are listed on our Lab Testing page. Check that the report names HGH Fragment 176-191 before you order. Regulatory status: the fragment is not an authorized drug in Canada, and growth-hormone fragments are on the World Anti-Doping Agency prohibited list. We sell it strictly as a laboratory reagent for in-vitro research.
What HGH Fragment 176-191 research looks at
- Adipocyte metabolism: lipolysis and lipogenesis in isolated fat cells.
- Separating GH effects: metabolic activity without IGF-1, insulin or growth signalling.
- Fragment comparisons: side-by-side work with AOD-9604.
- Structure-activity work: which parts of growth hormone carry which activities.
Why researchers order HGH Fragment 176-191 from Pure Peptides Canada
Add a 5 mg vial or a box of 10 above. Orders over $299 ship free across Canada.
See lab resultsHGH Fragment 176-191 FAQ
Where can I buy HGH Fragment 176-191 in Canada?
Pure Peptides Canada stocks HGH Fragment 176-191 as a lyophilized research reagent in 5 mg vials and ships it from inside Canada by tracked Xpresspost in 3–7 days ($25 CAD), or free in 4–12 days on orders over $299.
Is HGH Fragment 176-191 the same as growth hormone?
No. Full human growth hormone has 191 amino acids. This fragment contains only the last 16 and does not have growth hormone’s growth-promoting or IGF-1-raising activity in study models.
What is the difference between HGH Fragment 176-191 and AOD-9604?
They cover the same C-terminal region. AOD-9604 is the specific stabilized version developed and trialled by Metabolic Pharmaceuticals. Our AOD-9604 research guide explains the relationship and the trial results.
Can HGH Fragment 176-191 be used in people or animals?
No. This product is for in-vitro laboratory research only and is not a drug, supplement or food. We do not provide dosing or administration information.
For laboratory research use only. Not a drug, supplement, food or cosmetic, not for human or veterinary use, and not intended to diagnose, treat, cure or prevent any disease.
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