“GLP-1” is one of the most-asked topics in peptide research. This is a research-framed explainer of what these peptides are and how the popular ones differ. It makes no medical, weight-loss, or dosing claims.
What “GLP-1” means
GLP-1 stands for glucagon-like peptide-1, an incretin involved in glucose-related signalling. Peptides described as GLP-1 receptor agonists are molecules studied for how they interact with that receptor in metabolic research.
How the popular ones differ
| Peptide | Receptor targets studied |
|---|---|
| Semaglutide | GLP-1 (single agonist) |
| Tirzepatide | GLP-1 + GIP (dual agonist) |
| Retatrutide | GLP-1 + GIP + glucagon (triple agonist) |
Other compounds in this research area include cagrilintide (an amylin-analogue studied alongside GLP-1 agonists) and newer agents such as mazdutide and survodutide.
How they’re supplied and verified
- Form: lyophilized research peptides in sealed vials.
- Verification: batch-matched third-party COA with HPLC purity and MS identity.
- Use: in-vitro/laboratory research only — not therapeutics.
FAQ
What’s the difference between semaglutide and tirzepatide? In research terms, semaglutide is a single GLP-1 receptor agonist, while tirzepatide is a dual GLP-1/GIP agonist. Retatrutide adds a third target (glucagon).
Are these weight-loss drugs? They are sold here as research reagents, not medicines, and we make no medical or weight-loss claims. Their study belongs to metabolic research.
What is cagrilintide? An amylin-analogue peptide studied alongside GLP-1 receptor agonists in metabolic research.
Browse verified research peptides
Every batch we ship is independently tested by Janoshik Analytical (HPLC for purity, mass spectrometry for identity) with a batch-matched Certificate of Analysis you can verify. Browse the catalog → · See the latest COAs →
*For laboratory and research use only. Not for human or veterinary use, consumption, or administration. Nothing in this article is medical advice or a claim that any compound treats, cures, or prevents any condition. This is general information, not legal advice.*