BPC-157 is a synthetic 15-amino-acid peptide (a pentadecapeptide) whose sequence corresponds to a fragment of a protein found in human gastric juice. It is used as a test and reference compound in laboratory research, most often in preclinical models of tissue repair and gastrointestinal mucosa. BPC-157 is not an authorized drug in Canada or anywhere else, and everything on this page concerns its use as a laboratory research reagent.
Health Canada’s public advisory “Think twice before injecting peptides bought online” lists BPC-157 among the unauthorized peptide drugs that consumers should avoid (reference 5). BPC-157 sold here is a laboratory reagent and is not for injection or any other use in people or animals.
BPC-157 at a glance
| Property | Detail |
|---|---|
| Full name | Body Protection Compound-157 (BPC-157) |
| Type | Synthetic pentadecapeptide (15 amino acids) |
| Sequence | Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val (GEPPPGKPADDAGLV) |
| Molecular formula | C62H98N16O22 |
| Molecular weight | ≈ 1419.5 g/mol |
| Usual supplied form | Lyophilized powder in a sealed vial |
| Status | Not an authorized drug; sold for laboratory research use only |
What BPC-157 research covers
The published literature on BPC-157 is predominantly preclinical — cell-culture work and rodent models — and a large share of it comes from a single research group. Recurring topics include musculoskeletal soft-tissue models (tendon, ligament and muscle), gastrointestinal mucosa models, angiogenesis-related signalling and interactions with the nitric oxide system. Human clinical data are very limited, so findings from these models are best read as hypotheses for further laboratory work rather than as evidence of any effect in people.
In vitro, BPC-157 is typically used as a test or reference compound in cell-migration, proliferation and signalling assays, or as an analytical standard when developing HPLC and LC-MS methods for short peptides.
BPC-157 vs TB-500
BPC-157 and TB-500 are often discussed together in tissue-repair research, but they are unrelated molecules. BPC-157 is a 15-residue peptide of about 1.4 kDa; TB-500 refers to synthetic thymosin beta-4 (43 residues, about 4.96 kDa) or to fragments of it. See the full BPC-157 vs TB-500 comparison and the TB-500 research guide.
How to verify a BPC-157 batch
- Identity by mass spectrometry — the observed mass should match the theoretical mass of GEPPPGKPADDAGLV (≈ 1419.5 Da average mass; ≈ 1418.7 Da monoisotopic). A purity percentage on its own does not confirm identity.
- Purity by HPLC — look at the chromatogram, not only the headline number. The HPLC testing guide explains what to look for.
- Batch match — the lot number on the certificate must match the vial. Current and previous Janoshik reports for BPC-157 are listed on the lab testing page.
- Net peptide content — counter-ions and residual water mean peptide mass can be lower than vial fill weight. See how to read a peptide COA.
Storage and handling
Keep sealed lyophilized vials cold, dry and away from light, let a vial reach room temperature before opening, and aliquot reconstituted stock so it is not frozen and thawed repeatedly. Full detail is in the peptide storage guide.
Sourcing BPC-157 in Canada
Pure Peptides Canada supplies BPC-157 for laboratory research as lyophilized vials and in pre-combined blends with TB-500, KPV and GHK-Cu. Orders ship tracked from within Canada, and vial batches are matched to independent Janoshik reports.
Research-grade BPC-157, batch-tested
HPLC purity and mass-spec identity from Janoshik, matched to your lot. Tracked shipping across Canada.
Frequently asked questions
What is BPC-157?
A synthetic 15-amino-acid peptide (GEPPPGKPADDAGLV) whose sequence derives from a protein in human gastric juice. It is used as a research compound in laboratory models and is not an authorized drug.
What is the molecular weight of BPC-157?
About 1419.5 g/mol (molecular formula C62H98N16O22). Mass-spectrometry identity results for a batch should match this value.
Is BPC-157 the same as TB-500?
No. They are structurally unrelated peptides that are often discussed together. BPC-157 has 15 residues; thymosin beta-4, the basis of TB-500, has 43.
Can I buy BPC-157 in Canada?
Pure Peptides Canada sells BPC-157 as a laboratory reagent for research use only, shipped from within Canada. It is not for human or veterinary use, and buyers are responsible for complying with applicable Canadian regulations.
Do you provide dosing or administration guidance?
No. BPC-157 is supplied strictly for in-vitro laboratory research. We can answer questions about sequence, molecular weight, solubility, storage and analytical documentation.
For laboratory and research use only. Not for human or veterinary use, consumption, or administration. Nothing on this page is medical advice or a claim that any compound diagnoses, treats, cures, or prevents any condition. Purchasers confirm they are qualified to handle research materials and are of legal age in their province.
References
- Vasireddi N, Hahamyan H, Salata MJ, Karns M, Calcei JG, Voos JE, et al. Emerging use of BPC-157 in orthopaedic sports medicine: a systematic review. HSS Journal. 2025;21(4):485–495. Systematic review of 36 studies of BPC-157 in muscle, tendon, ligament and bone injury models; 35 were preclinical and one was clinical.
- Gwyer D, Wragg NM, Wilson SL. Gastric pentadecapeptide body protection compound BPC 157 and its role in accelerating musculoskeletal soft tissue healing. Cell and Tissue Research. 2019;377(2):153–159. Review of BPC-157 research in musculoskeletal soft-tissue models, noting that most studies used small rodents, many came from one research group, and the findings have not been confirmed in humans.
- Seiwerth S, Milavic M, Vukojevic J, Gojkovic S, Krezic I, Vuletic LB, et al. Stable gastric pentadecapeptide BPC 157 and wound healing. Frontiers in Pharmacology. 2021;12:627533. Review by the University of Zagreb group behind much of the BPC-157 literature, summarizing animal studies in skin, gastrointestinal, tendon, ligament, muscle and bone models and its reported interactions with the nitric oxide system.
- Sport Integrity Canada. Reminder: non-approved peptides included on the Prohibited List. News release, April 27, 2026. Notes that BPC-157 is classified as S0 (non-approved substances) on the World Anti-Doping Agency’s Prohibited List.
- Health Canada. Think twice before injecting peptides bought online: unauthorized products can seriously harm you. Public advisory, last updated April 9, 2026. Warns consumers about the health risks of unauthorized injectable peptide drugs sold online and lists BPC-157 among the peptides to avoid.
