IGF-1 LR3

Description

IGF-1 LR3 is a long-acting analog of insulin-like growth factor 1, stocked here as a lyophilized reagent for laboratories buying research peptides in Canada. It is used in vitro in cell culture and receptor signaling work where a stable IGF-1 analog is needed, and it is sold strictly as a research chemical — not as a drug, supplement or veterinary product.

Overview

Each unit is a sealed vial containing 1mg of IGF-1 LR3 as a lyophilized powder, ready to be reconstituted by the end user in a suitable research solvent and diluted to working concentration. The analog itself is a modified form of recombinant human IGF-1, carrying an arginine substitution at position three and a thirteen-residue N-terminal extension — the two changes that give it the “Long R3” designation and that account for its reduced affinity for IGF binding proteins compared with native IGF-1. It is listed under Growth & Signaling and is available as a single vial or as a box of ten for laboratories running longer studies or multiple concurrent plates.

What it is known for

Buyers choose this listing for the documentation behind it. Every batch is tested by Janoshik, an independent analytical laboratory, for purity by HPLC and identity by mass spectrometry, and the certificate of analysis you receive matches the batch in your hand rather than a generic file kept on the site. That matters with IGF-1 LR3 in particular: it is a larger, more complex molecule than the short synthetic peptides most suppliers stock, and a third-party chromatogram and mass confirmation are the only practical way for a buyer to know what arrived. Add Canadian-owned operations and domestic dispatch, and orders clear without international customs handling.

Key features

• Lyophilized powder format — The dried form is far more stable than a solution during transit and storage, so the reagent keeps its integrity until you decide when and in what solvent to reconstitute it.
• Third-party HPLC purity testing — Chromatographic purity from an outside lab tells you how much of the vial content is the target compound and how much is process-related impurity — the number that governs whether your dosing calculations are meaningful.
• Mass spectrometry identity confirmation — Purity alone does not prove the molecule is the one on the label. MS identity closes that gap, which matters for an analog like LR3 where a truncated or unmodified variant would behave differently in assay.
• Batch-matched certificate of analysis — You can cite specific analytical data for the exact lot used in your work, which is what reviewers, supervisors and internal QA ask for when results are questioned.
• Long R3 modification — The reduced binding-protein affinity that comes with the arginine substitution and N-terminal extension is why researchers select this analog over native IGF-1 in serum-containing culture systems.
• Single vial or box of ten — Buy one vial to validate the reagent in your system, then scale to a ten-pack of the same product line when you need consistent material across a longer protocol.
• Cold storage and tracked Canadian dispatch — The reagent is held cold and shipped domestically with tracking, so you can plan a receiving window rather than leaving a temperature-sensitive package sitting at a border.

Benefits

• You know what is in the vial before you open it, because the analytical work was done by a lab that does not sell the product.
• Reconstitution stays under your control — you choose solvent, concentration and volume to suit the assay rather than inheriting someone else’s dilution.
• Documentation is ready for lab records, method sections and internal purchasing review without a separate request.
• Domestic shipping keeps lead times predictable and avoids the delays and temperature exposure that come with cross-border parcels.
• Consistent supply from a single product line makes it easier to compare results across experiments run weeks apart.

Specifications

Typical applications

• In-vitro cell culture studies involving IGF-1 receptor signaling
• Comparative work against native IGF-1 in serum-containing media
• Assay development and reagent qualification in academic and biotech laboratories
• Analytical method work requiring a characterized peptide reference material

Important information

• Research use only. This product is not a drug, supplement, food or cosmetic, is not intended to diagnose, treat, cure or prevent any disease, and is not for human or veterinary use, ingestion or administration.
• Keep the vial cold and sealed on arrival, and reconstitute only when you are ready to begin work.
• Reconstitute in a solvent appropriate to your protocol and handle the peptide gently — vigorous agitation is best avoided with proteins of this size.
• Request or download the certificate of analysis for your lot and confirm the batch number printed on the vial matches it.
• Handle in a properly equipped laboratory using standard practices for research chemicals, and dispose of material according to your institution’s procedures.
• Purchase is intended for qualified research buyers: laboratories, universities, biotech companies and equivalent institutions.

Common questions

What form does it arrive in?

A sealed vial of lyophilized (freeze-dried) powder containing 1mg of IGF-1 LR3. It requires reconstitution in a suitable research solvent before use, at whatever concentration your protocol calls for.

Who performs the testing?

Janoshik, an independent analytical laboratory with no stake in the sale. Purity is assessed by HPLC and identity by mass spectrometry.

Is the certificate of analysis specific to my vial?

Yes. The COA is matched to the production batch the vial came from, not a general document representing a previous lot.

How is IGF-1 LR3 different from standard IGF-1?

It is an analog carrying an arginine substitution at position three and an additional thirteen-residue extension at the N-terminus. Those modifications reduce its affinity for IGF binding proteins, which is the property researchers are usually after when they select it for culture work.

Why buy the box of ten?

Ten vials from the same product line suit longer studies or parallel experiments where you want to avoid introducing a new variable partway through. Many labs start with a single vial to confirm the reagent performs in their system, then order the larger format.

Can this be used on humans or animals?

No. It is supplied for in-vitro laboratory research only and must not be ingested or administered to humans or animals under any circumstances.

In summary

A well-documented IGF-1 LR3 reagent for laboratories that want independent purity and identity data attached to the specific lot they are working with, supplied lyophilized in 1mg vials and shipped cold and tracked within Canada. Strictly research use only.