SS-31 (Elamipretide)

Description

SS-31 (Elamipretide) is a mitochondria-targeted tetrapeptide studied for its interaction with cardiolipin in the inner mitochondrial membrane, and it is one of the more frequently requested items among researchers sourcing research peptides in Canada for cellular bioenergetics and aging work. It is supplied here as a lyophilized powder for reconstitution in the laboratory, with third-party analytical documentation listed by batch on our Lab Testing page or available on request.

Overview

Each vial contains SS-31 (Elamipretide) as a lyophilized powder, sealed and ready for reconstitution in a solvent appropriate to the assay being run. Sizes are 10 mg, 30 mg and 50 mg, each available as a single vial or as a box of ten for laboratories running extended dose-response series, multiple cell lines or long timecourse work without changing lots mid-study. SS-31 belongs to the aromatic-cationic Szeto-Schiller peptide series, described in the literature as a short tetrapeptide with alternating aromatic and basic residues that concentrates in the inner mitochondrial membrane independently of membrane potential. That mechanism of localization is why it appears so often in mitochondrial research protocols rather than as a general cell-treatment compound. This item is a research reagent. It is not a drug, supplement, food or cosmetic, and it is not intended for human or veterinary use.

What it is known for

Buyers know SS-31 primarily as the mitochondria-targeted reference peptide in cellular aging and bioenergetics research — the compound reached for when the experimental question concerns the inner mitochondrial membrane specifically rather than cytosolic antioxidant activity. Within the Canadian supply picture, it is chosen here for the combination of independent Janoshik analysis, a certificate of analysis listed by batch on our Lab Testing page or available on request, and domestic shipping that keeps a cold-handled peptide from sitting in international customs queues.

Key features

• Third-party HPLC purity testing by Janoshik — Purity is tested by HPLC at Janoshik Analytical, a lab with no commercial stake in the result, so the figure on your COA is an independent measurement rather than a supplier’s own claim.
• Mass spectrometry identity confirmation — Confirms the material in the vial is the intended peptide and not a mislabelled or substituted sequence — the failure mode that quietly invalidates an entire study.
• Certificate of analysis — Janoshik Analytical reports are listed by batch on our Lab Testing page or available on request; match the batch number on your vial to its report.
• Lyophilized powder format — The dry state is far more stable than solution, so material holds during transit and storage and you control the solvent, concentration and buffer your protocol requires.
• Three fill weights (10 mg, 30 mg, 50 mg) — Lets you match the vial to the scale of the work — small fills for pilot and range-finding runs, larger fills to avoid repeated reconstitution and freeze-thaw cycles.
• Boxes of ten available in every size — Extended experiments and multi-arm studies can be run on a consistent supply, removing lot-to-lot variability as a confounding variable.
• Cold storage and tracked Canadian dispatch — Shipments stay domestic and trackable end to end, avoiding cross-border delays that leave a temperature-sensitive reagent in transit longer than it should be.
• Discreet, sealed packaging — Vials arrive intact and unlabelled to outside view, which suits shared receiving areas and shipping to institutional or home laboratory addresses alike.

Benefits

• You can document provenance and purity for your methods section without chasing paperwork after the fact.
• Reconstitution is on your terms — solvent, molarity and aliquoting all follow your protocol rather than a pre-mixed format.
• Consistent lots across a box of ten keep replicate experiments comparable.
• Domestic fulfilment shortens the window between order and bench, which matters for material kept cold.
• Buying the right fill weight avoids both wasted peptide and the freeze-thaw degradation that comes from repeatedly opening one oversized vial.

Specifications

Detail	Value
Compound	SS-31 (Elamipretide)
SKU	PP-SS31ELAMIPRETIDE
Category	Anti-Aging & Cellular
Physical form	Lyophilized powder for reconstitution
Sizes	10 mg, 30 mg, 50 mg — single vial or box of 10
Purity testing	HPLC, third-party (Janoshik)
Identity testing	Mass spectrometry, third-party (Janoshik)
Documentation	Certificate of analysis listed by batch on our Lab Testing page or available on request
Storage and shipping	Stored cold; shipped tracked from Canada
Intended use	In-vitro laboratory research only — not for human or veterinary use

Typical applications

• In-vitro investigation of mitochondrial function and cellular bioenergetics
• Cellular aging and senescence research models
• Cardiolipin and inner mitochondrial membrane studies
• Oxidative stress and mitochondrial dysfunction assay work
• Reference or comparator compound in mitochondria-targeted peptide screening

Important information

• Research use only. This product is not a drug, supplement, food or cosmetic, is not intended to diagnose, treat, cure or prevent any disease, and is not for human or veterinary use, ingestion or administration.
• Keep the vial cold and sealed until reconstitution; lyophilized peptide is considerably more stable dry than in solution.
• Choose a reconstitution solvent suited to your assay, and prepare single-use aliquots after reconstitution to limit freeze-thaw cycles.
• Request or download the certificate of analysis for your lot and file it with your experimental records before work begins.
• Handle with standard laboratory PPE and dispose of material according to your institution’s chemical waste procedures.
• For multi-stage or long-running studies, order a box of ten in one purchase so the whole study runs on comparable material.

Common questions

What form does SS-31 arrive in?

As a lyophilized powder sealed in a vial. You reconstitute it in the laboratory using a solvent appropriate to your protocol — nothing is supplied pre-mixed.

Is the certificate of analysis specific to my vial?

Each COA covers one tested batch. Testing is performed by Janoshik, an independent analytical lab, and the COA is listed by batch on our Lab Testing page or available on request.

What does the third-party testing actually cover?

HPLC for purity and mass spectrometry for identity — one confirms how much of the material is the target peptide, the other confirms it is the correct peptide.

Which size should I order?

Match it to your experimental scale. A 10 mg vial suits pilot and range-finding work; 30 mg and 50 mg reduce how often you reconstitute during larger studies. Boxes of ten are for extended or multi-arm work where lot consistency matters.

Where does it ship from and how long is it in transit?

Orders are dispatched from within Canada with nationwide tracking, so shipments stay domestic and do not pass through customs. Delivery time depends on the destination and carrier service.

Can this be used in or on humans or animals?

No. It is sold strictly as a laboratory research reagent for in-vitro use and is not a drug, supplement or veterinary product.

In summary

SS-31 (Elamipretide) supplied dry, tested independently, and documented lot by lot — the format researchers need when the mitochondrial question is the point of the experiment. Choose the fill weight that fits your study, keep it cold until reconstitution, and file the batch COA with your records.

Further reading: MOTS-c, SS-31 and humanin explained covers SS-31 (elamipretide) alongside the other mitochondria-targeted research peptides.