HGH Fragment 176-191: What the Growth Hormone Fragment Research Shows
HGH Fragment 176-191 is the C-terminal end of human growth hormone: its sequence, where the idea came from, what the studies found and what's unproven.
Archive
Category: Metabolic Research
Incretin and metabolic research explained: GLP-1, GIP and glucagon receptor agonists, amylin analogues, AMPK, brown adipose tissue and compounds such as AOD-9604 and 5-Amino-1MQ, with their status in Canada.
Amylin: The Other Hormone Beta Cells Release
Amylin explained: the 37-amino-acid hormone co-secreted with insulin, how it was found in pancreatic amyloid deposits, why the human form clumps, how its receptors are assembled, and the analogues now in trials.
Brown Adipose Tissue and Thermogenesis
How adult human brown fat was confirmed in 2009, what UCP1 actually does, why FDG-PET does not measure heat production, how little energy brown fat is measured to burn, and why none of the compounds sold as thermogenic acts on it.
Adipotide (FTPP): What the Research Shows
Adipotide (FTPP) explained: how the prohibitin-targeting peptide from MD Anderson was built, what the mouse and monkey studies found, the kidney findings and where it stands today.
AMPK: The Energy Sensor Behind Metabolic Peptide Research
What AMP-activated protein kinase is, how LKB1 and CaMKK2 switch it on, what it turns on and off, why metformin's AMPK link is still contested, and which research compounds genuinely act on it.
GIP Explained: The Incretin Hormone Discovered at UBC
GIP explained: the 42-amino-acid gut hormone discovered at UBC, how it boosts insulin, why it was renamed, and how tirzepatide and retatrutide target its receptor.
Retatrutide Phase 3 Results: What the TRIUMPH Trials Found
Retatrutide's phase 3 TRIUMPH results explained: weight loss across four trials, the dysesthesia signal, discontinuation rates, cardiovascular data and what comes next.
SLU-PP-332: What the ‘Exercise Mimetic’ Research Actually Shows
SLU-PP-332 explained: the estrogen-related receptor agonist behind the exercise-in-a-pill headlines, what the mouse studies found, and what has never been tested.
5-Amino-1MQ: What the NNMT Inhibitor Research Shows
5-Amino-1MQ explained: the small-molecule NNMT inhibitor, what the mouse obesity and aged-muscle studies found, why it isn't a peptide, and sourcing in Canada.
GLP-1 Peptides Explained: A Research Map from Semaglutide to Retatrutide
GLP-1 peptides explained: semaglutide, tirzepatide, retatrutide, mazdutide, survodutide, cagrilintide and orforglipron mapped by receptor, trial data and Canadian status.