HCG

Description

HCG (human chorionic gonadotropin) is a glycoprotein hormone widely used as a reference ligand in gonadotropin receptor and steroidogenesis work. This listing supplies it as a 1000iu lyophilized vial for laboratory research use only, shipped cold from within Canada — which matters if you have been sourcing research peptides in Canada from overseas vendors and losing weeks to customs and uncontrolled transit temperatures. It is not a drug or supplement and is not for human or veterinary use.

Overview

HCG is a heterodimeric glycoprotein made up of an alpha subunit shared with LH, FSH and TSH, and a beta subunit that is specific to chorionic gonadotropin and gives the molecule its distinct receptor behaviour and long circulating profile relative to LH. In the laboratory it is used as an agonist at the LH/CG receptor, which makes it a standard tool in Leydig and granulosa cell steroidogenesis assays, cAMP signalling studies and receptor binding work. It is supplied here as a sterile-filtered lyophilized powder in a sealed vial, potency stated in international units at 1000iu per vial, for reconstitution in a suitable research solvent immediately before use. Available as a single vial or a box of ten for labs running extended protocols or multiple arms from a single lot.

What it is known for

Buyers choose this listing for the paperwork behind it. Every batch is sent to Janoshik Analytical — an independent third-party lab, not an in-house bench — and tested for purity by HPLC and identity by mass spectrometry. The certificate of analysis is matched to the batch you receive, so the number on your vial corresponds to the document you cite, rather than a representative COA from an unrelated lot. Combined with domestic cold-chain dispatch from Canada, it removes the two variables that most often compromise gonadotropin reagents: unverified material and unmanaged transit temperature.

Key features

• Lyophilized powder format — Freeze-dried protein is far more stable in storage and transit than a solution, so the vial arrives with its structure intact and you control the concentration and buffer at the point of reconstitution.
• 1000iu stated potency per vial — Gonadotropin activity is expressed in international units rather than mass, letting you calculate working concentrations against the standard used across the published literature.
• Independent HPLC purity testing — Chromatographic purity from an outside lab tells you what fraction of the material is the target compound and whether degradation products or process residues are present — the difference between a clean dose-response curve and unexplained variance.
• Mass spectrometry identity confirmation — Confirms you have chorionic gonadotropin and not a mislabelled or substituted glycoprotein, which is the failure mode that quietly invalidates an entire assay series.
• Batch-matched certificate of analysis — You can record the specific lot and its analytical data in your methods, satisfying reproducibility requirements and internal QA without chasing documentation after the fact.
• Box of ten option — Ten vials drawn from one batch let you run a full study, or repeat it, without introducing lot-to-lot variation partway through your data.
• Cold storage and cold dispatch from Canada — The reagent is held and sent under refrigeration on a domestic tracked route, avoiding the extended border holds and unmonitored warehousing that degrade protein reagents shipped internationally.
• Discreet tracked shipping nationwide — Plain packaging with tracking to any Canadian address means the delivery can be logged into your inventory on arrival rather than sitting unaccounted for.

Benefits

• Analytical data from an independent lab, so purity and identity are documented rather than asserted
• Domestic cold-chain delivery shortens transit and keeps the material within a controlled temperature range
• One batch across multiple vials removes lot variation as a confounding factor in longer protocols
• Lyophilized supply gives you full control over solvent, buffer and final concentration
• Traceable lot numbering supports reproducibility and internal quality documentation

Specifications

Typical applications

• LH/CG receptor binding and agonist characterization studies
• Leydig cell and granulosa cell steroidogenesis assays
• cAMP and downstream signalling pathway investigation
• Glycoprotein hormone comparative and structural work
• Reference ligand or positive control in gonadotropin-related in-vitro models
• Assay development and immunoassay standard curve work

Important information

• Research use only. Not a drug, supplement, food or cosmetic. Not for human or veterinary use, ingestion or administration, and not intended to diagnose, treat, cure or prevent any disease.
• Store the sealed lyophilized vial cold and protected from light. Reconstitute only in a solvent appropriate to your protocol and immediately before use.
• Once reconstituted, keep the solution refrigerated and handle it as you would any protein reagent — avoid repeated freeze-thaw cycles and vigorous agitation, which shear glycoprotein structure.
• Direct the reconstitution solvent down the vial wall rather than onto the powder cake, and swirl rather than shake, to preserve the intact dimer.
• Request the certificate of analysis for your lot and record the batch number in your experimental notes before the vial is opened.
• Confirm the material is being received by a qualified laboratory or research buyer and handled under appropriate institutional controls.

Common questions

What does the third-party testing actually cover?

Janoshik, an independent analytical lab, runs HPLC to establish purity and mass spectrometry to confirm identity. The resulting certificate is tied to the batch of the vial you receive, so the data reflects your material rather than a general sample.

Why is potency given in iu instead of milligrams?

Gonadotropins are standardized by biological activity, not mass, because glycosylation varies and affects potency. International units are the convention across the literature, so 1000iu lets you match your working concentrations to published protocols directly.

What should I reconstitute it with?

Choose the solvent your protocol calls for — bacteriostatic or sterile water is common for glycoprotein reagents in vitro. The vial is supplied lyophilized specifically so the buffer and final concentration are yours to determine.

Does the single vial come from the same batch as the box of ten?

Each vial carries a lot number and the certificate is matched to it. If you need multiple vials from one lot for a continuous study, the box of ten is the reliable way to get it.

How is it shipped, and does it stay cold?

It is held in cold storage and dispatched from Canada in discreet packaging with tracking. Because it does not cross an international border, transit is shorter and the temperature exposure is far more predictable than with overseas shipments.

Can this be used on humans or animals?

No. It is supplied strictly for in-vitro laboratory research and is not manufactured, labelled or intended for human or veterinary administration in any form.

In summary

A 1000iu lyophilized HCG vial with independent HPLC and MS data behind it, batch-matched documentation, and cold domestic dispatch. If your work depends on a gonadotropin reagent whose identity and purity you can cite, this is the version that arrives with the evidence attached. Research use only.